Trial intelligence / Profile preview

Loncastuximab Tesirine + Acalabrutinib in CLL

NCT05971251Phase 1Active, not recruiting

Sponsor
University of Alabama at Birmingham
Start
Dec 2023
Primary completion
Dec 2026
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs)
Countries
1
01

Overview

Phase 1, open-label trial of loncastuximab tesirine in chronic lymphocytic leukemia (CLL) (4 arms), sponsored by University of Alabama at Birmingham. Primary endpoints: Maximum Tolerated Dose at 12 months and Dose-Limiting Toxicity at 42 days. Started Dec 2023; status: active, not recruiting.

02

Drugs

loncastuximab tesirine
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Conditions

chronic lymphocytic leukemia (CLL)

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