Trial intelligence / Profile preview

Glo-BNHL: Novel Agents in Paediatric and Adolescent Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

NCT05991388Phase 3Recruiting

Sponsor
University of Birmingham
Start
May 2024
Primary completion
May 2031
Modality
Gene Editing, Gene Silencing, Bispecific Antibodies
Countries
7
01

Overview

Phase 3, open-label trial of odronextamab, loncastuximab tesirine and CAR T-cells (Glo-BNHL) in B-cell non-Hodgkin lymphoma (3 arms), sponsored by University of Birmingham. Primary endpoints: Objective Response at cycle 3 and Complete Response at cycle 3. Started May 2024; status: recruiting.

02

Drugs

odronextamabloncastuximab tesirineCAR T-cells (Glo-BNHL)
03

Conditions

B-cell non-Hodgkin lymphoma

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