Trial intelligence / Profile preview

Vepdegestrant PK DDI with Carbamazepine

NCT06005688Phase 1Completed

Sponsor
Pfizer
Start
Aug 2023
Primary completion
Oct 2023
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of vepdegestrant in breast cancer, sponsored by Pfizer. Primary endpoints: Maximum Observed Plasma Concentration at 144 hours and Area Under the Curve From Time Zero to Extrapolated Infinite Time at 144 hours. Started Aug 2023; status: completed.

02

Drugs

vepdegestrant
03

Conditions

breast cancer

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