Trial intelligence / Profile preview

Durvalumab + Tremelimumab vs Pembrolizumab in 1L Metastatic Non-squamous NSCLC with STK11, KEAP1, or KRAS Mutations

NCT06008093Phase 2Active, not recruiting

Sponsor
AstraZeneca
Start
Apr 2024
Primary completion
Oct 2026
Modality
Antibody Conjugates, Engineered Antibody Formats, PD-1/PD-L1 Inhibitors
Countries
1
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Overview

Phase 2, randomised, open-label trial of durvalumab and tremelimumab in non-small cell lung cancer (NSCLC) (2 arms), sponsored by AstraZeneca. Primary endpoints: Progression-free survival at 48 months, Progression-free survival at 6 months and 1 more. Started Apr 2024; status: active, not recruiting.

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Drugs

durvalumabtremelimumab
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Conditions

non-small cell lung cancer (NSCLC)

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