Trial intelligence / Profile preview

Mosunetuzumab With Polatuzumab Vedotin and Lenalidomide in R/R DLBCL

NCT06015880Phase 1Recruiting

Sponsor
National Cancer Institute
Start
May 2024
Primary completion
Jun 2027
Modality
Bispecific Antibodies, Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of mosunetuzumab in diffuse large B-cell lymphoma (DLBCL), high grade B-cell lymphoma (HGBCL) and transformed indolent B-cell lymphoma, sponsored by National Cancer Institute. Primary endpoint: Safety and tolerability of mosunetuzumab+polatuzumab vedotin+lenalidomide for determination of recommended phase 2 dose. Started May 2024; status: recruiting.

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Drugs

mosunetuzumab
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Conditions

diffuse large B-cell lymphoma (DLBCL)high grade B-cell lymphoma (HGBCL)transformed indolent B-cell lymphoma

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