Trial intelligence / Profile preview

ALN-PNP in NAFLD with PNPLA3 Genetic Risk Factor

NCT06024408Phase 1Completed

Sponsor
Regeneron Pharmaceuticals
Start
May 2024
Primary completion
Jul 2025
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of pivicasiran in non-alcoholic fatty liver disease (NAFLD), sponsored by Regeneron Pharmaceuticals. Primary endpoints: Incidence of treatment-emergent adverse events up to 253 days and Severity of treatment-emergent adverse events up to 253 days. Started May 2024; status: completed.

02

Drugs

pivicasiran
03

Conditions

non-alcoholic fatty liver disease (NAFLD)

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