Trial intelligence / Profile preview

WOnDER-BT

NCT06058988Phase 2Recruiting

Sponsor
Memorial Sloan Kettering Cancer Center
Start
Sep 2023
Primary completion
Sep 2027
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs), Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of trastuzumab deruxtecan in brain cancer, glioblastoma (GBM), metastatic cancer and 1 more (3 cohorts), sponsored by Memorial Sloan Kettering Cancer Center. Primary endpoint: Intraoperative plasma concentrations in brain tumors after T-DXd injections up to 24 months. Started Sep 2023; status: recruiting.

02

Drugs

trastuzumab deruxtecan
03

Conditions

brain cancerglioblastoma (GBM)metastatic cancerleptomeningeal metastasis (LM)

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