Trial intelligence / Profile preview

Curcumin Versus Placebo in CCUS, LR-MDS, and MPNs

NCT06063486Phase 2Recruiting

Sponsor
University of Southern California
Start
Mar 2024
Primary completion
Dec 2026
Modality
Covalent Small Molecules, Classical Binding Small Molecules, Nucleic Acid-Directed Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of curcumin in clonal cytopenia of undetermined significance (CCUS), myelodysplastic syndrome (MDS) and Myeloproliferative Neoplasm (MPN) (2 arms), sponsored by University of Southern California. Primary endpoints: Mean change in peripheral blood levels of inflammatory cytokines at 12 months, Mean change in symptom scores for clonal cytopenia of undetermined significance and low risk myelodysplastic syndrome patients at 12 months and 1 more. Started Mar 2024; status: recruiting.

02

Drugs

curcumin
03

Conditions

clonal cytopenia of undetermined significance (CCUS)myelodysplastic syndrome (MDS)Myeloproliferative Neoplasm (MPN)

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