Trial intelligence / Profile preview

TDM-Based Atezolizumab Dosing in Cancer

NCT06066138Phase 1Recruiting

Sponsor
National Cancer Institute
Start
Nov 2025
Primary completion
Jan 2027
Modality
Monoclonal Antibodies
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of atezolizumab in alveolar soft part sarcoma (ASPS), non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC) and 2 more, sponsored by National Cancer Institute. Primary endpoint: Feasibility of reducing drug exposure while maintaining plasma drug concentration at 16 weeks. Started Nov 2025; status: recruiting.

02

Drugs

atezolizumab
03

Conditions

alveolar soft part sarcoma (ASPS)non-small cell lung cancer (NSCLC)small cell lung cancer (SCLC)hepatocellular carcinoma (HCC)melanoma

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