Trial intelligence / Profile preview

Hyperpolarized 13C-Pyruvate MRI in TBI and SAH

NCT06103201Phase 1Recruiting

Sponsor
University of Maryland, Baltimore
Start
Oct 2023
Primary completion
Nov 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of hyperpolarized 13C-pyruvate in traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) (3 arms), sponsored by University of Maryland, Baltimore. Primary endpoints: Apparent conversion rate constant pyruvate to lactate, Lactate-to-pyruvate ratio and 2 more. Started Oct 2023; status: recruiting.

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Drugs

hyperpolarized 13C-pyruvate
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Conditions

traumatic brain injury (TBI)subarachnoid hemorrhage (SAH)

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