Trial intelligence / Profile preview

Xevinapant with ChemoRT in Cisplatin-Ineligible Head and Neck Cancer

NCT06110195Phase 1Terminated

Sponsor
University of Chicago
Start
Jan 2024
Primary completion
May 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of xevinapant in squamous cell carcinoma of the head and neck (HNSCC) (5 arms), sponsored by University of Chicago. Primary endpoint: Best safe dose of xevinapant when given in combination with radiation and chemotherapy at 21 days. Started Jan 2024; status: terminated.

02

Drugs

xevinapant
03

Conditions

squamous cell carcinoma of the head and neck (HNSCC)

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