Trial intelligence / Profile preview

COCOON: Enhanced Dermatologic Management in EGFR-Mutated NSCLC Treated With Amivantamab + Lazertinib

NCT06120140Phase 2Active, not recruiting

Sponsor
Janssen Pharmaceutical
Start
Feb 2024
Primary completion
May 2027
Modality
Bispecific Antibodies, Monoclonal Antibodies
Countries
11
01

Overview

Phase 2, randomised, open-label trial of amivantamab and lazertinib in non-small cell lung cancer (NSCLC) (6 arms), sponsored by Janssen Pharmaceutical. Primary endpoint: Number of Participants With Grade Greater Than or Equal to (>=) 2 Dermatologic Adverse Events of Interest (DAEIs) at 12 weeks. Started Feb 2024; status: active, not recruiting.

02

Drugs

amivantamablazertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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