Trial intelligence / Profile preview

JNJ-88549968 in CALR-mutated Myeloproliferative Neoplasms

NCT06150157Phase 1Recruiting

Sponsor
Janssen Pharmaceutical
Start
Dec 2023
Primary completion
Jun 2027
Modality
Antibody Conjugates, Bispecific Antibodies, Monoclonal Antibodies
Countries
10
01

Overview

Phase 1, open-label, single-arm trial of JNJ-88549968 in essential thrombocythemia (ET) and myelofibrosis (MF), sponsored by Janssen Pharmaceutical. Primary endpoints: Dose Limiting Toxicity at 35 days, Adverse Events at 2 years and 1 more. Started Dec 2023; status: recruiting.

02

Drugs

JNJ-88549968
03

Conditions

essential thrombocythemia (ET)myelofibrosis (MF)

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