Trial intelligence / Profile preview

Platform Study of RAS(ON) Inhibitors in RAS-Mutated NSCLC and Solid Tumors

NCT06162221Phase 2Recruiting

Sponsor
Revolution Medicines
Start
Jan 2024
Primary completion
Jun 2027
Modality
Small Molecules, Cyclic Peptides
Countries
13
01

Overview

Phase 2, open-label trial of elironrasib, daraxonrasib and zoldonrasib in non-small cell lung cancer (NSCLC) and solid tumor (4 arms), sponsored by Revolution Medicines. Primary endpoints: Adverse events at 5 years and Dose limiting toxicities at 21 days. Started Jan 2024; status: recruiting.

02

Drugs

elironrasibdaraxonrasibzoldonrasib
03

Conditions

non-small cell lung cancer (NSCLC)solid tumor

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