Trial intelligence / Profile preview

Pirtobrutinib DDI with Repaglinide in Healthy Subjects

NCT06165146Phase 1Completed

Sponsor
Eli Lilly and Company
Start
Nov 2020
Primary completion
Dec 2020
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label, single-arm trial of pirtobrutinib in mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), sponsored by Eli Lilly and Company. Primary endpoints: Area Under the Concentration-time Curve, From Time 0 to the Last Measurable Concentration of Repaglinide at Day 12, Area Under the Concentration-time Curve From Time 0 Extrapolated to Infinity of Repaglinide at Day 12 and 13 more. Started Nov 2020; status: completed.

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Drugs

pirtobrutinib
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Conditions

mantle cell lymphoma (MCL)chronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)

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