Trial intelligence / Profile preview

BR1018B and BR1018C in Essential Hypertension and Primary Hypercholesterolemia

NCT06165250Phase 3

Key facts

Status
Completed
Start
Apr 2024
Primary completion
Nov 2025
Countries
1
Sponsor
Boryung
Conditions
essential hypertensionhypercholesterolemia
01

Overview

Phase 3, randomised, double-blind trial in essential hypertension and hypercholesterolemia comparing BR1018A-1 + BR1018B + BR1018C, BR1018A + BR1018B-1 + BR1018C and BR1018A-1 + BR1018B + BR1018C-1 (3 arms). Primary endpoints: Mean sitting systolic blood pressure at 8 weeks and Low-density lipoprotein cholesterol at 8 weeks. Started Apr 2024; status: completed.

02

Design

3 arms
Study design
RandomizedDouble-blind
  • BR1018A-1 + BR1018B + BR1018C

    Experimental arm

  • BR1018A + BR1018B-1 + BR1018C

    Active comparator arm

  • BR1018A-1 + BR1018B + BR1018C-1

    Active comparator arm

03

Who it enrols

Patients with essential hypertension and primary hypercholesterolemia, with specific blood pressure and lipid profile criteria.

04

Endpoints

Primary

  • Mean sitting systolic blood pressure

  • Low-density lipoprotein cholesterol

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