Trial intelligence / Profile preview

Infusional FOLFOX Plus Camrelizumab and Apatinib Versus HAIC-FOLFOX Plus Camrelizumab and Apatinib for Hepatocellular Carcinoma

NCT06172205Phase 3Recruiting

Sponsor
Sun Yat-sen Memorial Hospital
Start
Jul 2023
Primary completion
Jul 2028
Modality
Immune Checkpoint Inhibitors, DNA Intercalators/Alkylators, Orthosteric Ligands
Countries
1
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Overview

Phase 3, randomised, open-label trial of oxaliplatin, folinic acid, fluorouracil, camrelizumab and Rivoceranib in hepatocellular carcinoma (HCC) (2 arms), sponsored by Sun Yat-sen Memorial Hospital. Primary endpoints: 6-month Progression-Free Survival Rate and Hepatic Reserve Function Impairment Rate (ICG-15min) up to 3 years. Started Jul 2023; status: recruiting.

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Drugs

oxaliplatinfolinic acidfluorouracilcamrelizumabRivoceranib
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Conditions

hepatocellular carcinoma (HCC)

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