Trial intelligence / Profile preview

RestorAATion-1: SAD and MAD Study of WVE-006 in Healthy Participants

NCT06186492Phase 1Completed

Sponsor
Wave Life Sciences
Start
Nov 2023
Primary completion
Feb 2025
Modality
Small Interfering RNA (siRNA), Modified DNA Oligonucleotides, Single-strand DNA
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of WVE-006 in alpha-1 antitrypsin deficiency (AATD) (7 arms), sponsored by Wave Life Sciences. Primary endpoint: Proportion of Participants With Adverse Events. Started Nov 2023; status: completed.

02

Drugs

WVE-006
03

Conditions

alpha-1 antitrypsin deficiency (AATD)

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