Trial intelligence / Profile preview

89Zr-Brentuximab Imaging in CD30+ Lymphoma

NCT06186986Phase 3Not yet recruiting

Sponsor
University Medical Center Groningen
Start
Jan 2024
Primary completion
Jan 2025
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs), Small Molecules
01

Overview

Phase 3, open-label trial of brentuximab vedotin in Hodgkin lymphoma (HL), T-cell non-Hodgkin lymphoma, cutaneous T-cell lymphoma (CTCL) and 1 more (2 cohorts), sponsored by University Medical Center Groningen. Primary endpoints: Optimized 89Zr-brentuximab imaging protocol for visualisation of CD30 distribution by PET-scan at 2 years, Safety profile of the 89Zr-brentuximab tracer at 2 years and 1 more. Planned start Jan 2024; status: not yet recruiting.

02

Drugs

brentuximab vedotin
03

Conditions

Hodgkin lymphoma (HL)T-cell non-Hodgkin lymphomacutaneous T-cell lymphoma (CTCL)diffuse large B-cell lymphoma (DLBCL)

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