Trial intelligence / Profile preview

Brimarafenib + Panitumumab in Advanced RAS Mutant CRC and PDAC

NCT06194877Phase 1Terminated

Sponsor
MapKure, LLC
Start
Apr 2024
Primary completion
Mar 2025
Modality
Small Molecules
Countries
2
01

Overview

Phase 1, open-label trial of Brimarafenib in colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC) (3 arms), sponsored by MapKure, LLC. Primary endpoints: Number of Participants with Serious Adverse Events up to 2 years, Number of Participants with Treatment-emergent Adverse Events up to 2 years and 6 more. Started Apr 2024; status: terminated.

02

Drugs

Brimarafenib
03

Conditions

colorectal cancer (CRC)pancreatic ductal adenocarcinoma (PDAC)

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