Trial intelligence / Profile preview

RV591: Ad26.Mos4.HIV and CH505 TF chTrimer Vaccine Study

NCT06205056Phase 1Recruiting

Sponsor
U.S. Army Medical Research and Development Command
Start
Jan 2024
Primary completion
Dec 2025
Modality
Prophylactic Vaccines, Recombinant Proteins and Enzymes, DNA Vaccines
Countries
1
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Overview

Phase 1, randomised, double-blind trial of CH505 TF chTrimer + ALFQ and Ad26.Mos4.HIV in human immunodeficiency virus infection (HIV) (4 arms), sponsored by U.S. Army Medical Research and Development Command. Primary endpoints: Occurrence and severity of solicited local and systemic adverse events, Occurrence, severity, and relationship to vaccination of unsolicited adverse events and 2 more. Started Jan 2024; status: recruiting.

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Drugs

CH505 TF chTrimer + ALFQAd26.Mos4.HIV
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Conditions

human immunodeficiency virus infection (HIV)

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