Trial intelligence / Profile preview

LOXO-305 Drug Interaction Study with CYP Substrates

NCT06215430Phase 1Completed

Sponsor
Eli Lilly and Company
Start
Jan 2021
Primary completion
Apr 2021
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of pirtobrutinib in mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), sponsored by Eli Lilly and Company. Primary endpoints: Area Under the Concentration Time Curve From Hour 0 to 24 Hours Post-Dose, Area Under the Concentration-time Curve From Hour 0 to the Last Measurable Concentration at Day 15 and 10 more. Started Jan 2021; status: completed.

02

Drugs

pirtobrutinib
03

Conditions

mantle cell lymphoma (MCL)chronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)

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