Trial intelligence / Profile preview

Ruxolitinib Plus Fostamatinib in Steroid Refractory Chronic GvHD

NCT06233110Phase 1Recruiting

Start
Oct 2025
Primary completion
Jan 2029
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, open-label trial of fostamatinib in chronic graft-versus-host disease (cGVHD) (6 arms). Primary endpoint: Minimum safe and biologically effective dose at 6 months. Started Oct 2025; status: recruiting.

02

Drugs

fostamatinib
03

Conditions

chronic graft-versus-host disease (cGVHD)

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