Trial intelligence / Profile preview

Carfilzomib and Sotorasib in KRASG12C Mutated Advanced NSCLC

NCT06249282Phase 1Recruiting

Sponsor
City of Hope
Start
Apr 2024
Primary completion
Nov 2026
Modality
Irreversible Covalent Inhibitors, Reversible Covalent Inhibitors
Countries
1
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Overview

Phase 1, open-label, single-arm trial of carfilzomib in non-small cell lung cancer (NSCLC), sponsored by City of Hope. Primary endpoints: Incidence of dose limiting toxicities at 28 days and Incidence of grade 3 and 4 treatment-related toxicities. Started Apr 2024; status: recruiting.

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Drugs

carfilzomib
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Conditions

non-small cell lung cancer (NSCLC)

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