Trial intelligence / Profile preview

pCCLCHIM-p47 in p47 AR-CGD

NCT06253507Phase 2Enrolling by invitation

Sponsor
National Institute of Allergy and Infectious Diseases
Start
Jun 2024
Primary completion
Mar 2027
Countries
1
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Overview

Phase 2, open-label, single-arm trial of Cryopreserved Autologous CD34+ cells transduced with pCCLCHIM-p47 in chronic granulomatous disease (CGD), sponsored by National Institute of Allergy and Infectious Diseases. Primary endpoint: Engraftment of genetically modified cells at 6 months. Started Jun 2024; status: enrolling by invitation.

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Drugs

Cryopreserved Autologous CD34+ cells transduced with pCCLCHIM-p47
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Conditions

chronic granulomatous disease (CGD)

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