Trial intelligence / Profile preview

Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 and CH505 TF chTrimer HIV Vaccines

NCT06267872Phase 1Withdrawn

Sponsor
National Institute of Allergy and Infectious Diseases
Start
Oct 2024
Primary completion
Dec 2025
Modality
Recombinant Proteins and Enzymes, Nanoparticles, Vaccines & Immunotherapeutics
Countries
2
01

Overview

Phase 1, open-label trial of CD4BS CH505M5 Pr-NP1 and CH505 TF chTrimer + ALFQ in human immunodeficiency virus infection (HIV) (7 arms), sponsored by National Institute of Allergy and Infectious Diseases. Primary endpoints: Frequency of local reactogenicity signs and symptoms at Day 239, Frequency of systemic reactogenicity signs and symptoms at Day 239 and 7 more. Planned start Oct 2024; status: withdrawn.

02

Drugs

CD4BS CH505M5 Pr-NP1CH505 TF chTrimer + ALFQ
03

Conditions

human immunodeficiency virus infection (HIV)

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