Trial intelligence / Profile preview

Pharmacokinetics of [14C]-DNL343 in Healthy Males

NCT06281158Phase 1Completed

Sponsor
Denali Therapeutics Inc.
Start
Mar 2024
Primary completion
Apr 2024
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of DNL343 in amyotrophic lateral sclerosis (ALS), sponsored by Denali Therapeutics Inc. Primary endpoints: Area Under the Curve from Time Zero to Infinity at 28 days, Area Under the Curve from Time Zero to the Last Measurable Concentration at 28 days and 6 more. Started Mar 2024; status: completed.

02

Drugs

DNL343
03

Conditions

amyotrophic lateral sclerosis (ALS)

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