Trial intelligence / Profile preview

DCC-3084 in Advanced Malignancies Driven by the MAPK Pathway

NCT06287463Phase 1Terminated

Sponsor
Deciphera Pharmaceuticals
Start
May 2024
Primary completion
Feb 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of dcc-3084 in solid tumor (advanced stage), non-small cell lung cancer (NSCLC), pancreatic ductal adenocarcinoma (PDAC) and 2 more (2 arms), sponsored by Deciphera Pharmaceuticals. Primary endpoints: Number of Participants with Dose-limiting Toxicities at 28 days and Objective Response Rate at 24 months. Started May 2024; status: terminated.

02

Drugs

dcc-3084
03

Conditions

solid tumor (advanced stage)non-small cell lung cancer (NSCLC)pancreatic ductal adenocarcinoma (PDAC)melanomacastration-resistant prostate cancer (CRPC)

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