Trial intelligence / Profile preview

PK Interaction of Sevabertinib with Dabigatran and Rosuvastatin

NCT06329895Phase 1Completed

Sponsor
Bayer
Start
Mar 2024
Primary completion
Jun 2024
Modality
Fragment-Derived Small Molecules, Allosteric Modulators, Orthosteric Ligands
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of sevabertinib in non-small cell lung cancer (NSCLC), sponsored by Bayer. Primary endpoints: Maximum observed concentration of unconjugated dabigatran at Day 9, Area under the curve of unconjugated dabigatran at Day 9 and 2 more. Started Mar 2024; status: completed.

02

Drugs

sevabertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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