Trial intelligence / Profile preview

Biomarkers for Neoadjuvant Therapies in MIBC

NCT06341478Recruiting

Sponsor
IRCCS Ospedale San Raffaele
Start
Mar 2024
Primary completion
Mar 2026
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes, Antibody-Drug Conjugates (ADCs)
Countries
1
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Overview

Open-label trial of sacituzumab govitecan, pembrolizumab, nivolumab and paclitaxel in muscle-invasive bladder cancer (MIBC) (4 arms), sponsored by IRCCS Ospedale San Raffaele. Primary endpoints: Predictors of immune response to experimental combination therapies in MIBC, Genomic predictors of response to experimental combination therapies in MIBC and 1 more. Started Mar 2024; status: recruiting.

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Drugs

sacituzumab govitecanpembrolizumabnivolumabpaclitaxel
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Conditions

muscle-invasive bladder cancer (MIBC)

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