Trial intelligence / Profile preview

CD19-BAFF CAR-T for R/R B-cell ALL and NHL

NCT06346912Phase 1Recruiting

Sponsor
Zhejiang University
Start
May 2024
Primary completion
May 2027
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of CD19-BAFF CAR-T in B cell acute lymphoblastic leukemia (B-ALL) and B-cell non-Hodgkin lymphoma, sponsored by Zhejiang University. Primary endpoints: Dose-limiting toxicity at 28 years and Treatment-emergent adverse events at 2 years. Started May 2024; status: recruiting.

02

Drugs

CD19-BAFF CAR-T
03

Conditions

B cell acute lymphoblastic leukemia (B-ALL)B-cell non-Hodgkin lymphoma

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