Trial intelligence / Profile preview

129Xe MRI/MRS to Monitor Sotatercept Response in PAH

NCT06351345Phase 2Recruiting

Start
Oct 2025
Primary completion
Feb 2029
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of hyperpolarized xenon gas in pulmonary arterial hypertension (PAH). Primary endpoints: Change in Xenon MRI Red Blood Cell (RBC) percentage at 12 months and Change in cardiogenic oscillation amplitudes at 12 months. Started Oct 2025; status: recruiting.

02

Drugs

hyperpolarized xenon gas
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Conditions

pulmonary arterial hypertension (PAH)

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