Trial intelligence / Profile preview

IA Carboplatin + Caelyx vs IA Carboplatin + Etoposide Phosphate in Recurrent GBM

NCT06356883Phase 2Recruiting

Sponsor
Université de Sherbrooke
Start
Aug 2025
Primary completion
Apr 2027
Modality
Targeted Liposomes, Stealth (PEGylated) Liposomes, Conventional Liposomes
Countries
1
01

Overview

Phase 2, randomised, open-label trial in glioblastoma (GBM) comparing IA Carboplatin + IA Caelyx with IA Carboplatin + IA Etoposide Phosphate (2 arms). Primary endpoints: Tumor Response on MRI using the RANO Criteria and Progression-free Survival. Started Aug 2025; status: recruiting.

02

Drugs

pegylated liposomal doxorubicinetoposide phosphate
03

Conditions

glioblastoma (GBM)

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