Trial intelligence / Profile preview

Dato-DXd + Rilvegostomig or Rilvegostomig vs Pembrolizumab in 1L Advanced Non-squamous NSCLC

NCT06357533Phase 3Recruiting

Sponsor
AstraZeneca
Start
Apr 2024
Primary completion
Dec 2029
Modality
Monoclonal Antibodies, Bispecific Antibodies, Antibody-Drug Conjugates (ADCs)
Countries
21
01

Overview

Phase 3, randomised, open-label trial of datopotamab deruxtecan and rilvegostomig in non-small cell lung cancer (NSCLC) (3 arms), sponsored by AstraZeneca. Primary endpoints: Progression-Free Survival in TROP2 biomarker positive participants at 4 years and Overall Survival in TROP2 biomarker positive participants at 6 years. Started Apr 2024; status: recruiting.

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Drugs

datopotamab deruxtecanrilvegostomig
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Conditions

non-small cell lung cancer (NSCLC)

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