Trial intelligence / Profile preview

Rechallenge with Dabrafenib and Trametinib in BRAF-positive Anaplastic Thyroid Cancer

NCT06362694Phase 2Recruiting

Sponsor
Saint Petersburg State University
Start
Mar 2024
Primary completion
Mar 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of dabrafenib + trametinib and trametinib in anaplastic thyroid cancer (ATC), sponsored by Saint Petersburg State University. Primary endpoints: Objective Response Rate, Progression-Free Survival at 2 years and 1 more. Started Mar 2024; status: recruiting.

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Drugs

dabrafenib + trametinibtrametinib
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Conditions

anaplastic thyroid cancer (ATC)

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