Trial intelligence / Profile preview

Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer

NCT06379217Phase 1Active, not recruiting

Sponsor
Novartis
Start
Jul 2024
Primary completion
Oct 2026
Modality
Small Molecules, Peptide-Drug Conjugates
Countries
5
01

Overview

Phase 1, open-label trial of lutetium lu 177 vipivotide tetraxetan, lutetium Lu 177 dotatate and AAA503 in Prostatic Neuroendocrine Carcinoma (NEPC) (3 arms), sponsored by Novartis. Primary endpoints: Number/extent of lesions with at least a moderate uptake of any of the Radioligand Imaging (RLI) and Percentage changes in quantitative PET parameters. Started Jul 2024; status: active, not recruiting.

02

Drugs

lutetium lu 177 vipivotide tetraxetanlutetium Lu 177 dotatateAAA503
03

Conditions

Prostatic Neuroendocrine Carcinoma (NEPC)

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