Trial intelligence / Profile preview

Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

NCT06412198Phase 2Recruiting

Sponsor
University of Texas MD Anderson Cancer Center
Start
Aug 2024
Primary completion
Mar 2029
Modality
Immune Checkpoint Inhibitors, Antibody Conjugates, Engineered Antibody Formats
Countries
1
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Overview

Phase 2, open-label trial of adagrasib, KL-140 and cemiplimab in colorectal cancer (CRC) (2 arms), sponsored by University of Texas MD Anderson Cancer Center. Primary endpoints: Safety and adverse events and Objective Response Rate. Started Aug 2024; status: recruiting.

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Drugs

adagrasibKL-140cemiplimab
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Conditions

colorectal cancer (CRC)

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