Trial intelligence / Profile preview

NaV1.8 Inhibitors (VX-150, Suzetrigine, VX-993) Mechanistic Study in Healthy Adults

NCT06420765Phase 1Completed

Sponsor
Vertex Pharmaceuticals
Start
May 2024
Primary completion
Mar 2025
Modality
Prodrugs/Conditional Activator Small Molecules
Countries
1
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Overview

Phase 1, randomised, double-blind trial of VX-150, suzetrigine and VX-993 in pain (4 arms), sponsored by Vertex Pharmaceuticals. Primary endpoint: Change From Baseline in Activity Dependent Slowing. Started May 2024; status: completed.

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Drugs

VX-150suzetrigineVX-993
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Conditions

pain

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