Trial intelligence / Profile preview

VERVE-201 in Refractory Hyperlipidemia

NCT06451770Phase 1Recruiting

Sponsor
Verve Therapeutics
Start
Oct 2024
Primary completion
Dec 2027
Modality
Gene Silencing, CRISPR-Cas9, Lipid-based Nanoparticles
Countries
6
01

Overview

Phase 1, open-label trial of VERVE-201 in hypercholesterolemia and Refractory hypertriglyceridemia (rHTG) (3 arms), sponsored by Verve Therapeutics. Primary endpoint: Incidence of treatment-emergent adverse events (TEAEs) and serious adverse events (SAEs) at 365 days. Started Oct 2024; status: recruiting.

02

Drugs

VERVE-201
03

Conditions

hypercholesterolemiaRefractory hypertriglyceridemia (rHTG)

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