Trial intelligence / Profile preview

Cetuximab + Chemotherapy in ctDNA Negative Liver Metastatic CRC

NCT06490913Phase 2

Key facts

Status
Not yet recruiting
Start
Nov 2024
Primary completion
Jun 2025
Sponsor
Fujian Medical University Cancer Hospital
Modality
Engineered Antibody Formats, Antibody Conjugates, Monoclonal Antibodies
Conditions
colorectal cancer (CRC)
01

Overview

Phase 2, open-label, single-arm trial of cetuximab in colorectal cancer (CRC), sponsored by Fujian Medical University Cancer Hospital. Primary endpoint: Objective Response Rate. Planned start Nov 2024; status: not yet recruiting.

02

Design

1 arm
Study design
Non-randomizedOpen-labelSingle group
  • cetuximab+chemotherapy

    XELOX 1 cycle; cetuximab+chemotherapy up to 12 cycles

03

Who it enrols

Patients with liver metastases from RAS wild-type colorectal cancer and ctDNA superselective negative genes who have not received prior treatment.

04

Endpoints

Primary

  • Objective Response Rate

Secondary

  • Overall Survival

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