Trial intelligence / Profile preview

Intrathecal Pemetrexed, High-dose Furmonertinib, and Bevacizumab for EGFR-mutant NSCLC with Leptomeningeal Metastases

NCT06537297Phase 2Not yet recruiting

Sponsor
Hunan Cancer Hospital
Start
Sep 2024
Primary completion
Aug 2025
Modality
Small Molecules, Monoclonal Antibodies
Countries
1
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Overview

Phase 2, open-label, single-arm trial of pemetrexed, furmonertinib and bevacizumab in non-small cell lung cancer (NSCLC), sponsored by Hunan Cancer Hospital. Primary endpoint: Leptomeningeal Metastases Overall Survival up to 24 months. Planned start Sep 2024; status: not yet recruiting.

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Drugs

pemetrexedfurmonertinibbevacizumab
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Conditions

non-small cell lung cancer (NSCLC)

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