Trial intelligence / Profile preview

Methotrexate in Myeloproliferative Neoplasms

NCT06541249Phase 2Recruiting

Sponsor
Icahn School of Medicine at Mount Sinai
Start
Oct 2024
Primary completion
Jun 2027
Modality
Orthosteric Ligands
Countries
1
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Overview

Phase 2, open-label trial of methotrexate in polycythemia vera (PV), essential thrombocythemia (ET) and myelofibrosis (MF) (3 arms), sponsored by Icahn School of Medicine at Mount Sinai. Primary endpoints: Myelofibrosis Overall Response Rate at 24 weeks and Polycythemia Vera and Essential Thrombocythemia Overall Response Rate at 24 weeks. Started Oct 2024; status: recruiting.

02

Drugs

methotrexate
03

Conditions

polycythemia vera (PV)essential thrombocythemia (ET)myelofibrosis (MF)

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