Trial intelligence / Profile preview

[177Lu]Lu-NNS309 in Advanced Pancreatic, Lung, Breast and Colorectal Cancers

NCT06562192Phase 1Recruiting

Sponsor
Novartis
Start
Oct 2024
Primary completion
Jan 2031
Modality
Antibody-Radionuclide Conjugates, Peptide-Drug Conjugates
Countries
10
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Overview

Phase 1, open-label, single-arm trial of [177Lu]Lu-NNS309 in pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), breast cancer and 2 more, sponsored by Novartis. Primary endpoints: Dose Limiting Toxicities at 6 weeks, Adverse Events and Serious Adverse Events at 42 months and 2 more. Started Oct 2024; status: recruiting.

02

Drugs

[177Lu]Lu-NNS309
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Conditions

pancreatic ductal adenocarcinoma (PDAC)non-small cell lung cancer (NSCLC)breast cancertriple-negative breast cancer (TNBC)colorectal cancer (CRC)

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