Trial intelligence / Profile preview

Povetacicept in Adults With Immunoglobulin A Nephropathy (RAINIER)

NCT06564142Phase 3Active, not recruiting

Sponsor
Vertex Pharmaceuticals
Start
Aug 2024
Primary completion
Jan 2028
Modality
Antibody Fragments, Fc-Fusion Proteins
Countries
33
01

Overview

Phase 3, randomised, double-blind trial in immunoglobulin A nephropathy (IgAN) comparing Povetacicept with Placebo (2 arms). Primary endpoints: Change From Baseline in 24-hour Urine Protein to Creatinine Ratio at 36 weeks and Total Estimated Glomerular Filtration Rate Slope at 104 weeks. Started Aug 2024; status: active, not recruiting.

02

Drugs

povetacicept
03

Conditions

immunoglobulin A nephropathy (IgAN)

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