Trial intelligence / Profile preview

Bioavailability of BMS-986435 Tablet Formulations in Healthy Adults

NCT06577259Phase 1Completed

Sponsor
Bristol Myers Squibb
Start
Sep 2024
Primary completion
Feb 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 1, randomised, open-label trial of BMS-986435 in heart failure with preserved ejection fraction (HFpEF) and hypertrophic cardiomyopathy (HCM) (3 arms), sponsored by Bristol Myers Squibb. Primary endpoints: Maximum observed plasma concentration up to 105 days, Area under the plasma concentration-time curve from time zero to time of the last quantifiable concentration up to 105 days and 1 more. Started Sep 2024; status: completed.

02

Drugs

BMS-986435
03

Conditions

heart failure with preserved ejection fraction (HFpEF)hypertrophic cardiomyopathy (HCM)

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