Trial intelligence / Profile preview

AZD0022 Monotherapy and in Combination With Cetuximab in KRASG12D Mutated Tumours

NCT06599502Phase 1Terminated

Sponsor
AstraZeneca
Start
Oct 2024
Primary completion
Oct 2025
Modality
Small Molecules
Countries
4
01

Overview

Phase 1, randomised, open-label trial of AZD0022 in solid tumor (advanced stage), non-small cell lung cancer (NSCLC), pancreatic ductal adenocarcinoma (PDAC) and 1 more (7 arms), sponsored by AstraZeneca. Primary endpoints: Dose-Limiting Toxicity, Adverse Events and 2 more. Started Oct 2024; status: terminated.

02

Drugs

AZD0022
03

Conditions

solid tumor (advanced stage)non-small cell lung cancer (NSCLC)pancreatic ductal adenocarcinoma (PDAC)colorectal cancer (CRC)

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