Trial intelligence / Profile preview

Loncastuximab Tesirine and Rituximab Following SRS in CNS Lymphomas

NCT06607549Phase 1Recruiting

Sponsor
University of Utah
Start
Mar 2025
Primary completion
Nov 2029
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs)
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of loncastuximab tesirine in central nervous system lymphoma and diffuse large B-cell lymphoma (DLBCL), sponsored by University of Utah. Primary endpoint: Maximum Tolerated Dose / Safe and Tolerable Dose at 5 years. Started Mar 2025; status: recruiting.

02

Drugs

loncastuximab tesirine
03

Conditions

central nervous system lymphomadiffuse large B-cell lymphoma (DLBCL)

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