Trial intelligence / Profile preview

5G-EMERALD: Amivantamab in High Grade Malignant Brain Tumours

NCT06632236Phase 1Active, not recruiting

Sponsor
The Institute of Cancer Research
Start
Oct 2024
Primary completion
Jul 2027
Modality
Bispecific Antibodies, Monoclonal Antibodies
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of amivantamab in glioblastoma (GBM), astrocytoma and diffuse hemispheric glioma (DHG), sponsored by The Institute of Cancer Research. Primary endpoints: Safety and Tolerability at 18 months and Preliminary Antitumour Activity at 18 months. Started Oct 2024; status: active, not recruiting.

02

Drugs

amivantamab
03

Conditions

glioblastoma (GBM)astrocytomadiffuse hemispheric glioma (DHG)

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