Trial intelligence / Profile preview

Bioavailability of vepdegestrant variant tablet in healthy adults

NCT06645938Phase 1Completed

Sponsor
Pfizer
Start
Oct 2024
Primary completion
Feb 2025
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
1
01

Overview

Phase 1, randomised, open-label trial of vepdegestrant in breast cancer (2 arms), sponsored by Pfizer. Primary endpoints: Maximum Observed Plasma Concentration at 168 hours and Area Under the Curve From Time Zero to Extrapolated Infinite Time at 168 hours. Started Oct 2024; status: completed.

02

Drugs

vepdegestrant
03

Conditions

breast cancer

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