Trial intelligence / Profile preview

ATRA-based Chemo-free Bridging/Maintenance in CAR-T for High-risk R/R B-NHL

NCT06646666Phase 2Not yet recruiting

Sponsor
Ruijin Hospital
Start
Dec 2024
Primary completion
Jun 2027
Modality
Fragment-Derived Small Molecules, Reversible Covalent Inhibitors, Bivalent/Multivalent Binders
Countries
1
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Overview

Phase 2, open-label, single-arm trial of RJ CAR-T 002, tretinoin and zanubrutinib in B-cell non-Hodgkin lymphoma, sponsored by Ruijin Hospital. Primary endpoint: Complete Response Rate at 3 months. Planned start Dec 2024; status: not yet recruiting.

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Drugs

RJ CAR-T 002tretinoinzanubrutinib
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Conditions

B-cell non-Hodgkin lymphoma

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